Related Experiment Video
Updated: Jan 23, 2026

Author Spotlight: Improved Imaging for Neovascular Development in Congenital Heart Disease Research
Published on: April 26, 2024
Association Between Titration Method and Outcomes of First Night Satisfaction and CPAP Compliance
Sinem Nedime Sökücü1, Şenay Aydin2, Erdal İn3
1Department of Pulmonary Medicine, Yedikule Teaching Hospital for Pulmonology and Thoracic Surgery, İstanbul, Turkey.
Introduction:
The gold standard therapy for obstructive sleep apnoea syndrome (OSAS) is continuous positive airway pressure (CPAP). Our study evaluated the relationship between first night satisfaction and CPAP compliance, and the effect of using the titration method in this relationship.
Methods:
Between January 2012 and December 2012, 40 patients with the diagnosis of OSAS and without comorbidities, who had undergone CPAP titration, were included. Of these, 20 patients had undergone manual titration (MT) with polysomnography, whereas 20 patients had undergone auto-adjusted CPAP (APAP) titration. Questionnaires were administered during the morning of the titration night. The first-year adherence to treatment and patient compliance were evaluated.
Results:
Forty patients were randomised in two groups; 35 patients who could procure the CPAP and were available at the end of the first year completed the study. From the 35 patients, 20 (6 males; 40%) were in the MT group while 15 (6 males; 30%) were in the APAP group. No significant difference was detected between the mean titration pressure levels obtained with the MT or APAP group. There was no difference in terms of responses to the questions on the questionnaire between the two groups. At the first-year evaluation, no significant difference was detected between the groups.
Conclusions:
The titration method used to detect CPAP pressure, MT, or APAP does not affect patient satisfaction on the day following the titration night, and does not affect first-year compliance.
Related Concept Videos
Titration of a Polyprotic Acid
Nightmares and Night Terrors
Nightmares...
Precipitation Titration: Endpoint Detection Methods
In the Volhard method, a standard excess of AgNO3 is first added to the...
Acid-Base Titration Curves
For a titration carried out for 25.00 mL of...
Titration Calculations: Weak Acid - Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:
Restless Leg Syndrome and Night Terrors
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...

