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Proteolytic degradation of insulin and glucagon in rat brain during ontogenesis
M Reiser1, H G Bernstein, S Ansorge
1Institute of Neurobiology and Brain Research, Academy of Sciences, GDR, Magdeburg.
Acta Histochemica
|January 1, 1987
Abstract:
The degradation of insulin and glucagon was investigated in rat brain, kidney, and liver during postnatal ontogenesis. It was found that a maximal activity around 13 d is unique for CNS and differs remarkably from time-course in liver and kidney. It is concluded that this result supports the hypothesis of a growth promoting role of insulin in developing rat brain.