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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
[Obesity and Cancer].
Béatrice Lauby-Secretan1, Laure Dossus2, Claire Marant-Micallef3
1Centre international de Recherche sur le Cancer, Groupe Handbooks du CIRC, 150, cours Albert-Thomas, 69372 Lyon cedex 08, France.
Rising global obesity is linked to increased cancer risk. Excess weight contributes significantly to cancer cases, impacting prognosis and increasing adult cancer risk from childhood obesity.
Area of Science:
- Public Health
- Epidemiology
- Oncology
Background:
- Global prevalence of overweight and obesity is increasing in adults and children.
- In France, 49% of adults were overweight and 17% obese in 2015.
- Overweight and obesity are established risk factors for 13 cancer types.
Purpose of the Study:
- To highlight the link between excess weight and cancer incidence and prognosis.
- To quantify the burden of cancer attributable to excess weight in France.
- To emphasize the role of diet and physical activity in obesity prevention.
Main Methods:
- Analysis of epidemiological data on overweight and obesity prevalence.
- Review of International Agency for Research on Cancer (IARC) evaluations on cancer risk factors.
- Estimation of cancer cases attributable to excess weight in France.
Main Results:
- In France, 5.4% of cancer cases (18,600) in 2015 were attributed to excess weight.
- Specific cancer burdens include colon (3400), kidney (2600), breast (4500), and endometrial (2500).
- Obesity is associated with poorer prognosis in breast and colon cancers.
Conclusions:
- Excess weight is a significant contributor to cancer incidence and mortality.
- Obesity prevention through balanced diet and physical activity is crucial.
- Addressing childhood obesity is vital to reduce future adult cancer risk.
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