Related Experiment Video
Updated: Jan 23, 2026
08:26
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
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A Multicenter Study Evaluating Natural Orifice Specimen Extraction Surgery for Rectal Cancer
Zheng Liu1, Sergey Efetov2, Xu Guan1
1Department of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
The Journal of Surgical Research
|June 24, 2019
Summary
Natural orifice specimen extraction surgery (NOSES) is a safe and feasible alternative to conventional laparoscopic resection for rectal cancer, with comparable short-term outcomes. Further research is needed to confirm long-term benefits.
Area of Science:
- Surgical Oncology
- Minimally Invasive Surgery
- Colorectal Surgery
Background:
- Laparoscopic low anterior resection is common for rectal cancer.
- Natural orifice specimen extraction surgery (NOSES) offers a scarless approach.
- NOSES is an alternative to conventional laparoscopic resection (CLR).
Purpose of the Study:
- To evaluate the safety and feasibility of NOSES.
- To compare short-term outcomes of NOSES versus CLR for rectal cancer.
- To analyze outcomes in a multicenter retrospective study.
Main Methods:
- Retrospective analysis of 768 patients with rectal cancer (356 NOSES, 412 CLR).
- Data collected: demographics, operative parameters, postoperative complications.
- Procedures performed between January 2015 and December 2017 at three centers.
Main Results:
- No significant differences in operative time, lymph node retrieval, or intraoperative complications.
- Similar rates of positive resection margins, time to first flatus/defecation, and hospital stay.
- NOSES showed a trend towards fewer incisional hernias/wound infections compared to CLR, though not statistically significant.
Conclusions:
- NOSES is a viable alternative to CLR for rectal cancer.
- Short-term outcomes are comparable between NOSES and CLR.
- Long-term benefits of NOSES require further investigation.
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