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Chronic prostatitis: current treatment options.

Giacomo Maria Pirola1, Tiziano Verdacchi1, Stefano Rosadi1

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Research and Reports in Urology
|June 27, 2019
PubMed
Summary
This summary is machine-generated.

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men presents diverse symptoms impacting quality of life. This review focuses on non-bacterial CP/CPPS, exploring multifactorial causes beyond infection.

Keywords:
chronic pelvic pain syndromechronic prostatitispharmacological treatmentphysical therapypudendal neuralgia

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Area of Science:

  • Urology
  • Pain Medicine

Background:

  • Male chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a complex condition with varied symptoms affecting patients' quality of life.
  • Diagnosis and treatment are challenging due to the heterogeneity of symptoms and multifactorial nature of the disease.

Purpose of the Study:

  • To review chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men, focusing on cases where infectious causes have been excluded.
  • To highlight the multifactorial aspects of CP/CPPS, including autoimmunity, inflammation, myofascial tenderness, neuroinflammation, and psychological factors.

Main Methods:

  • This narrative review synthesizes current understanding of CP/CPPS.
  • Focuses on differential diagnoses and symptom investigation, excluding infectious prostatitis.

Main Results:

  • CP/CPPS is increasingly viewed as a multifactorial condition, not solely related to benign prostatic enlargement.
  • Key contributing factors include autoimmune responses, inflammation, myofascial pain, neuroinflammation, and psychological elements.
  • Symptoms span urinary, genital, rectal, and perineal areas, necessitating thorough investigation and consideration of differential diagnoses like pudendal nerve entrapment.

Conclusions:

  • Effective management of CP/CPPS requires recognizing its multifactorial etiology and excluding infectious causes.
  • A comprehensive approach investigating various contributing factors and differential diagnoses is crucial for patient care.