Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integrative transcriptomic profiling links telomere dysfunction to cGAS-STING activation in heart failure signatures in mice and humans.

Cardiovascular research·2026

Same author

Endocrine response in cardiogenic shock complicating myocardial infarction: the prognostic value of growth hormone and IGF-1.

The Journal of endocrinology·2025

Same author

Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction.

Radiology. Cardiothoracic imaging·2024

Same author

Angiotensin Receptor-Neprilysin Inhibition (Sacubitril/Valsartan) Reduces Structural Arterial Stiffness in Middle-Aged Mice.

Journal of the American Heart Association·2024

Same author

Ethanol Enhances Endothelial Rigidity by Targeting VE-Cadherin-Implications for Acute Aortic Dissection.

Journal of clinical medicine·2023

Same author

Abdominal Aortic Endograft Implantation Immediately Induces Vascular Stiffness Gradients That May Promote Adverse Aortic Neck Dilatation: Results of A Porcine <i>Ex Vivo</i> Study.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists·2023

Same journal

Exploring the Role of Hypusine Signaling in Vascular Smooth Muscle Cells for Mitigating Restenosis in Coronary Artery Disease.

Arteriosclerosis, thrombosis, and vascular biology·2026

Same journal

Circulating Extracellular Mitochondria Perpetuate Endothelial Damage via Cardiolipin-Mediated Mitophagic Overload.

Arteriosclerosis, thrombosis, and vascular biology·2026

Same journal

Myeloid Cell-Specific Deletion of LGR4 Suppresses Atherosclerotic Lesion Formation.

Arteriosclerosis, thrombosis, and vascular biology·2026

Same journal

Building Resilience in Academic Science and Medicine.

Arteriosclerosis, thrombosis, and vascular biology·2026

Same journal

Endothelial Continuum and Capillary Specialization in Pulmonary Vascular Development.

Arteriosclerosis, thrombosis, and vascular biology·2026

Same journal

Systematic Review and Meta-Analysis Examining the Effect of Upregulation and Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9 in Mouse Models of Abdominal Aortic Aneurysm.

Arteriosclerosis, thrombosis, and vascular biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 23, 2026

Identification of Fatty Acids in Bacillus cereus

Identification of Fatty Acids in Bacillus cereus

Published on: December 5, 2016

The Hardest Part.

Isabel N Schellinger^1,2, Karin Mattern^1,3, Uwe Raaz^1,3

¹From the Molecular and Translational Vascular Medicine, Department of Cardiology and Pneumology, Heart Center at the University Medical Center Göttingen, Germany (I.N.S., K.M., U.R.).

Arteriosclerosis, Thrombosis, and Vascular Biology

|June 27, 2019

Summary

This summary is machine-generated.

Understanding healthy aging is key as lifespans extend globally. This review explores arterial stiffening, a core aspect of vascular aging, and its impact on cardiovascular health in later life.

Keywords:

arterial stiffness cardiovascular diseases extracellular matrix healthy aging morbidity mortality risk factors

More Related Videos

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

Published on: February 10, 2023

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Published on: September 15, 2023

Related Experiment Videos

Last Updated: Jan 23, 2026

Identification of Fatty Acids in Bacillus cereus

Identification of Fatty Acids in Bacillus cereus

Published on: December 5, 2016

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

Published on: February 10, 2023

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Author Spotlight: Advancements in Cultivating Mouse Hair Cells for Auditory Research

Published on: September 15, 2023

Area of Science:

Gerontology
Cardiovascular Science
Vascular Biology

Background:

Global populations are living longer, increasing the importance of understanding aging.
Cardiovascular diseases are a major cause of morbidity and mortality in older adults.
Vascular aging, particularly arterial stiffening, is a critical factor in age-related cardiovascular disease.

Purpose of the Study:

To review the structural mechanisms of arterial stiffening.
To examine the functional implications of arterial stiffening for vascular aging.
To connect arterial stiffening to the concept of healthy aging.

Main Methods:

Literature review focusing on structural changes in arteries with age.
Analysis of functional consequences of arterial stiffening.
Synthesis of findings related to cardiovascular risk in aging.

Main Results:

Arterial stiffening is a primary structural change in vascular aging.
Increased arterial stiffness impairs cardiovascular function and increases disease risk.
Understanding these mechanisms is crucial for promoting healthy aging.

Conclusions:

Arterial stiffening is a key manifestation of vascular aging.
Addressing arterial stiffening is vital for maintaining cardiovascular health in aging individuals.
This knowledge supports the paradigm shift towards viewing aging as an opportunity for extended health.