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Anemia at Discharge From the PICU: A Bicenter Descriptive Study
Pierre Demaret1,2, Frédéric V Valla3, Hélène Behal4
1Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHC, Liège, Belgium.
Anemia is common in children leaving the pediatric intensive care unit (PICU). Anemia at PICU admission is a key predictor of discharge anemia, with specific risk factors varying by age.
Area of Science:
- Pediatric critical care medicine
- Hematology
- Epidemiology
Background:
- Anemia is a frequent complication in critically ill children.
- Understanding anemia prevalence and risk factors at pediatric intensive care unit (PICU) discharge is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of anemia at PICU discharge.
- To identify risk markers associated with anemia at PICU discharge in children.
Main Methods:
- A bicenter retrospective cohort study was conducted.
- Data from 3,170 children admitted to two French PICUs over five years were analyzed.
- Anemia was defined using World Health Organization criteria.
Main Results:
- 58.9% of children were anemic at PICU discharge.
- Anemia at PICU admission was the strongest predictor of discharge anemia, with age-dependent associations.
- Factors influencing anemia risk included red blood cell transfusions, age, creatinine levels, platelet count, C-reactive protein, plasma transfusions, and mechanical ventilation.
Conclusions:
- Anemia is prevalent upon discharge from the PICU.
- Anemia status at PICU admission helps stratify risk for discharge anemia.
- Further research is needed to elucidate the causes and outcomes of post-PICU anemia.
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