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Computed tomography: pathologic correlation in lung disease due to tocainide
M G Stein1, T Demarco, G Gamsu
1Department of Radiology, University of California, San Francisco 94143.
The American Review of Respiratory Disease
|February 1, 1988
Abstract:
High resolution computed tomography (CT) was used to demonstrate the active lung phase of a patient with tocainide pulmonary toxicity. Gallium uptake in the lungs, an interstitial pneumonitis with alveolar macrophages on transbronchial biopsy, and reversal of process with discontinuation of the drug indicate a pulmonary drug reaction. The high resolution CT scan defined alveolar and interstitial components to the lung abnormality and correlated closely with the pathologic findings. High resolution CT is a useful method for demonstration of fine lung morphology.