Related Experiment Video
Updated: Jan 22, 2026

Inhibition of Wound Epidermis Formation via Full Skin Flap Surgery During Axolotl Limb Regeneration
Published on: June 24, 2020
Emerging and innovative approaches for wound healing and skin regeneration: Current status and advances
Dimple Chouhan1, Namit Dey1, Nandana Bhardwaj2
1Biomaterial and Tissue Engineering Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
Abstract:
Current advances in skin tissue engineering and wound healing augur well for the development of split or full thickness skin substitutes to recapitulating the native functional skin. These engineered skin substitutes have fared successfully in recent years with exploration of various emerging technologies. As a result, recent clinical practice has been highly evolved incorporating various engineered skin substitutes as an adjunct to accelerate healing and improvement of quality of life in long-term. This review seeks to bring the researchers through various emerging and innovative approaches being developed and utilized for accelerating wound healing and skin regeneration. In order to attempt this, we reviewed various design considerations for skin repair and impact of several smart technologies viz., in situ 3D printing, portable bioprinters, electrosprayers and in situ forming hydrogels that have significantly improved wound healing and skin therapeutics. Furthermore, numerous cellular therapies such as effect of immunomodulation, stromal vascular fraction treatments, micro RNA (miRNA) and small interfering RNA (siRNA) based skin therapeutics have been thoroughly discussed. Finally, an update of clinical trials along with critical analysis of properties and benefits of different emerging technologies in healing certain types of wounds, prime challenges and future prospects in skin tissue engineering are discussed.
Related Concept Videos
Emerging Adulthood
Introduction Cardiac Emergencies
Marcia's Theory of Identity Status
Electrical Current
Extraction: Advanced Methods
Overview of Advanced Functional Groups
Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.

