Catalytically Active Imine-based Covalent Organic Frameworks for Detoxification of Nerve Agent Simulants in Aqueous
Sergio Royuela1,2, Rodrigo Gil-San Millán3, María J Mancheño4
1Departamento de Química Orgánica I, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain. s.royuela@ucm.es.
Abstract:
A series of imine-based covalent organic frameworks decorated in their cavities with different alkynyl, pyrrolidine, and N-methylpyrrolidine functional groups have been synthetized. These materials exhibit catalytic activity in aqueous media for the hydrolytic detoxification of nerve agents, as exemplified with nerve gas simulant diisopropylfluorophosphate (DIFP). These preliminary results suggest imine-based covalent organic frameworks (COFs) as promising materials for detoxification of highly toxic molecules.
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