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Updated: Aug 11, 2026

Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
Published on: April 17, 2017
Long-term mechanical ventilation in infants with neuromuscular disease
1Divisions of Pediatric Neurology, Children's Hospital Medical Center, Cincinnati, OH 45229.
Abstract:
Seven children with neuromuscular disease were placed on mechanical ventilation before the age of 2 years. The outcome for these patients was variable and did not correlate with primary diagnosis. There appeared to be a high correlation between the incidence of electrocardiogram changes and death. Our experience demonstrates that there was a high mortality rate (57%) in neuromuscular patients supported by mechanical ventilation before the age of 2 years.
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