Jove
Visualize
Contact Us

Related Concept Videos

Solution Formation02:16

Solution Formation

36.9K
There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride.
This selective...
36.9K
Social Traps01:41

Social Traps

26.3K
Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned...
26.3K
General Properties of Solutions02:12

General Properties of Solutions

35.5K
Many common substances around us exist as a solution, such as ocean water, air, and gasoline. All solutions are mixtures of substances that are composed of varying amounts of two or more types of atoms or molecules. A mixture with a non-uniform composition is a heterogeneous mixture, whereas a mixture with a uniform composition is a homogeneous mixture. The components that make the homogeneous mixture are evenly spread out and thoroughly mixed. 
35.5K
Ideal Solutions02:24

Ideal Solutions

22.3K
According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
22.3K
Electrolyte and Nonelectrolyte Solutions02:21

Electrolyte and Nonelectrolyte Solutions

71.3K
Substances that undergo either a physical or a chemical change in solution to yield ions that can conduct electricity are called electrolytes. If a substance yields ions in solution, that is, if the compound undergoes 100% dissociation, then the substance is a strong electrolyte. Complete dissociation is indicated by a single forward arrow. For example, water-soluble ionic compounds like sodium chloride dissociate into sodium cations and chloride anions in aqueous solution.
71.3K
Intermolecular Forces in Solutions02:28

Intermolecular Forces in Solutions

38.9K
The formation of a solution is an example of a spontaneous process, a process that occurs under specified conditions without energy from some external source.
When the strengths of the intermolecular forces of attraction between solute and solvent species in a solution are no different than those present in the separated components, the solution is formed with no accompanying energy change. Such a solution is called an ideal solution. A mixture of ideal gases (or gases such as helium and argon,...
38.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Direct measurement of the attractive electrosolvation force between a pair of colloidal particles.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same author

Measurements of molecular size and shape on a chip.

Science (New York, N.Y.)·2025
Same author

Chemical control of colloidal self-assembly driven by the electrosolvation force.

Nature communications·2025
Same author

Surface polarization strongly influences electrostatics in a nonlocal medium.

The Journal of chemical physics·2025
Same author

Sensing the structural and conformational properties of single-stranded nucleic acids using electrometry and molecular simulations.

Scientific reports·2024
Same author

A charge-dependent long-ranged force drives tailored assembly of matter in solution.

Nature nanotechnology·2024
Same journal

Function through shape: An overview of DNA G-quadruplexes in transcriptional regulation.

Current opinion in chemical biology·2026
Same journal

Advances in tools and technologies for multiplexed bioluminescence imaging.

Current opinion in chemical biology·2026
Same journal

High-resolution molecular mapping by expansion-coupled label-free and multimodal imaging.

Current opinion in chemical biology·2026
Same journal

Recent advances in glycoconjugate-based therapeutics.

Current opinion in chemical biology·2026
Same journal

Towards better red emitters for bioimaging: Innovations in rhodamine and cyanine chemistry.

Current opinion in chemical biology·2026
Same journal

Chemigenetic fluorescent biosensors in biological imaging - New trends and advances.

Current opinion in chemical biology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 22, 2026

Automated System for Single Molecule Fluorescence Measurements of Surface-immobilized Biomolecules
10:57

Automated System for Single Molecule Fluorescence Measurements of Surface-immobilized Biomolecules

Published on: November 2, 2009

13.2K

Single-molecule trapping and measurement in solution.

Maria I Bespalova1, Sushanta Mahanta1, Madhavi Krishnan1

  • 1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QZ, United Kingdom.

Current Opinion in Chemical Biology
|June 30, 2019
PubMed
Summary
This summary is machine-generated.

Single molecule trapping in solution is now achievable using diverse physical, optical, and thermodynamic methods. These techniques enable precise measurements of molecular properties, advancing single-molecule studies.

More Related Videos

Making Precise and Accurate Single-Molecule FRET Measurements using the Open-Source smfBox
07:12

Making Precise and Accurate Single-Molecule FRET Measurements using the Open-Source smfBox

Published on: July 5, 2021

3.9K
Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

5.2K

Related Experiment Videos

Last Updated: Jan 22, 2026

Automated System for Single Molecule Fluorescence Measurements of Surface-immobilized Biomolecules
10:57

Automated System for Single Molecule Fluorescence Measurements of Surface-immobilized Biomolecules

Published on: November 2, 2009

13.2K
Making Precise and Accurate Single-Molecule FRET Measurements using the Open-Source smfBox
07:12

Making Precise and Accurate Single-Molecule FRET Measurements using the Open-Source smfBox

Published on: July 5, 2021

3.9K
Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

5.2K

Area of Science:

  • Physical Chemistry
  • Nanotechnology
  • Molecular Biophysics

Background:

  • Single molecule trapping in the gas phase was established decades before fluid-phase techniques.
  • Solution-phase single molecule trapping presented unique challenges compared to gas-phase methods.
  • Recent advancements have overcome key obstacles in confining nanometer-scale entities in solution.

Purpose of the Study:

  • To review and categorize current methods for single molecule trapping in the fluid phase.
  • To highlight the diverse approaches enabling the confinement of molecules in solution.
  • To discuss the implications of these trapping techniques for molecular property measurements.

Main Methods:

  • Physical entrapment methods for molecular confinement.
  • Electrokinetic and optical techniques for nanometer-scale entity manipulation.
  • Thermodynamic approaches for achieving molecular trapping in solution.

Main Results:

  • A variety of techniques for trapping single molecules in solution are now available.
  • These methods are increasingly utilized in diverse single-molecule studies.
  • Specific trapping techniques facilitate highly precise and accurate measurements of molecular properties.

Conclusions:

  • Single molecule trapping in the fluid phase has matured significantly.
  • The proliferation of trapping techniques expands research possibilities in molecular science.
  • Advanced trapping methods offer new avenues for detailed molecular characterization in solution.