Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drag Force and Terminal Speed01:18

Drag Force and Terminal Speed

3.3K
An interesting force in everyday life is the force of drag on an object when it is moving in a fluid. Like friction, the drag force always opposes the motion of an object. Unlike simple friction, the drag force is proportional to some function of the velocity of the object in that fluid. This functionality is complicated and depends upon the shape of the object, its size, its velocity, and the fluid it is in. For most large objects, such as cyclists, cars, and baseballs, that are not moving too...
3.3K
Atomic Force Microscopy01:08

Atomic Force Microscopy

4.4K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
4.4K
Atomic Orbitals02:44

Atomic Orbitals

43.4K
An atomic orbital represents the three-dimensional regions in an atom where an electron has the highest probability to reside. The radial distribution function indicates the total probability of finding an electron within the thin shell at a distance r from the nucleus. The atomic orbitals have distinct shapes which are determined by l, the angular momentum quantum number. The orbitals are often drawn with a boundary surface, enclosing densest regions of the cloud.
43.4K
Intermolecular Forces03:13

Intermolecular Forces

70.4K
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
70.4K
Atomic Mass01:52

Atomic Mass

69.7K
Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
69.7K
The Atomic Theory of Matter02:59

The Atomic Theory of Matter

127.0K
The earliest recorded discussion of the basic structure of matter comes from ancient Greek philosophers. Leucippus and Democritus argued that all matter was composed of small, finite particles that they called atomos, meaning “indivisible.” Later, Aristotle and others came to the conclusion that matter consisted of various combinations of the four “elements” — fire, earth, air, and water — and could be infinitely divided. Interestingly, these philosophers...
127.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Confined Cationic Covalent Organic Cages Enable Oxidant-Free Hofmann-Löffler-Freytag/Cyclization Sequences.

Angewandte Chemie (International ed. in English)·2026
Same author

Effects of traditional Chinese exercises on sleep quality among post-stroke survivors: A systematic review and meta-analysis.

Complementary therapies in medicine·2026
Same author

Evaluation of the performance of reverse transcription-recombinase polymerase amplification (RT-RPA) coupled with CRISPR/Cas12a and microfluidics for one-step detection of common HCV genotypes.

Diagnostic microbiology and infectious disease·2026
Same author

Author Correction: Hidden states and dynamics of fractional fillings in twisted MoTe<sub>2</sub> bilayers.

Nature·2026
Same author

Strong Lateral Mode Confinement by Embedding SiO<sub>2</sub> Nanospheres in the DBRs of GaN-Based VCSELs.

Micromachines·2026
Same author

EXPRESS: RIN1 inhibited TRPV1-dependent pain sensitization in a mouse model of bone cancer pain.

Molecular pain·2026
Same journal

A compact low-power magnetic particle imaging scanner based on a permanent-magnet field-free-line generator with high gradient.

The Review of scientific instruments·2026
Same journal

Achieving ultrahigh resolution with high efficiency: Optical design of the two-dimensional Resonant Inelastic X-ray Scattering (2D-RIXS) spectrometer at NanoTerasu beamline 02U.

The Review of scientific instruments·2026
Same journal

Automated laboratory x-ray diffractometer and fluorescence spectrometer for high-throughput materials characterization.

The Review of scientific instruments·2026
Same journal

Nonlinear Bayesian Doppler tomography for simultaneous reconstruction of flow and temperature.

The Review of scientific instruments·2026
Same journal

A Reflectance-based multimodal wearable photoplethysmography (PPG) sensor.

The Review of scientific instruments·2026
Same journal

Temporal analysis of products-Raman (TAP-Raman): An integrated setup for operando spectroscopy and transient kinetic analysis.

The Review of scientific instruments·2026
See all related articles

Related Experiment Video

Updated: Jan 22, 2026

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope
06:45

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Published on: February 28, 2019

9.4K

High-speed atomic force microscope with a combined tip-sample scanning architecture.

Lu Liu1, Sen Wu1, Hai Pang2

  • 1State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China.

The Review of Scientific Instruments
|July 1, 2019
PubMed
Summary
This summary is machine-generated.

A novel high-speed atomic force microscope (HS-AFM) achieves 100 Hz line rates using a tip-sample combined scanning architecture. This advanced HS-AFM design enhances dynamic performance and sample handling capabilities.

More Related Videos

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM
08:31

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM

Published on: February 10, 2021

7.4K
Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells
09:27

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

4.4K

Related Experiment Videos

Last Updated: Jan 22, 2026

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope
06:45

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Published on: February 28, 2019

9.4K
Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM
08:31

Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope AFM-SECM

Published on: February 10, 2021

7.4K
Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells
09:27

Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells

Published on: April 2, 2021

4.4K

Area of Science:

  • Surface Science
  • Microscopy Technology
  • Nanotechnology

Background:

  • Atomic Force Microscopy (AFM) is crucial for nanoscale imaging.
  • Conventional AFMs often face limitations in scanning speed and sample manipulation.
  • High-speed imaging is essential for observing dynamic processes at the nanoscale.

Purpose of the Study:

  • To develop and present a novel high-speed atomic force microscope (HS-AFM).
  • To improve scanning speed and dynamic performance compared to existing AFM systems.
  • To enable robust imaging of larger and heavier samples.

Main Methods:

  • Implemented a tip-sample combined scanning architecture.
  • Separated the X-scanner (sample stage) from the AFM head containing Y and Z scanners.
  • Enhanced the optical beam deflection method for wide-range probe tracking.
  • Utilized a novel probe holder for easy probe exchange and alignment.

Main Results:

  • Achieved a line rate of up to 100 Hz using proportional-integral-derivative control and linear driving.
  • Demonstrated improved dynamic performance and carrying capacity due to scanner separation.
  • Confirmed the system's capability to handle samples up to several centimeters in size and over 40 g in mass.

Conclusions:

  • The presented HS-AFM design significantly enhances scanning speed.
  • The architecture offers superior dynamic performance and sample handling.
  • This technology advances the potential for real-time nanoscale observations and material analysis.