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Updated: Jan 22, 2026

Exfoliation and Analysis of Large-area, Air-Sensitive Two-Dimensional Materials
Published on: January 5, 2019
Development of enhanced sensitivity protocols on the RapidHIT™ 200 with a view to processing casework material
David Shackleton1, Jenny Pagram2, Nicholas Andrews1
1Key Forensic Services, 4 Penfold Drive, Wymondham, Norfolk NR18 0WZ, UK.
Abstract:
The RapidHIT™ 200 device from IntegenX® provides a sample-to-profile platform that is capable of processing a variety of sample types. In this study we review the sensitivity of the 'Run Other' protocol for processing crime stain type samples containing various input quantities of DNA using the AmpFℓSTR® NGMSElect™ Express PCR Amplification Kit cartridges available from IntegenX®. The range of DNA inputs which achieved useable results were not as desired and therefore various enhancements to the instruments extraction processes were investigated. These studies showed an improvement in the range of DNA input templates that could by processed on the RapidHIT™ 200 by using the enhanced methods and resulted in three new run protocols.
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