Related Experiment Video

Updated: Jan 22, 2026

Intravital Microscopy of the Inguinal Lymph Node
07:34

Intravital Microscopy of the Inguinal Lymph Node

Published on: April 4, 2011

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The achilles heel of minimally invasive inguinal lymph node dissection: Seroma formation

Nicolas Contreras1, James W Jakub1

  • 1Department of Surgery, Mayo Clinic, Rochester, MN, USA.

American Journal of Surgery
|July 2, 2019
PubMed
Abstract

Insights

Post-operative seroma remains a significant complication after minimally invasive inguinal lymph node dissection (MILND). Current interventions have not successfully reduced seroma rates, necessitating further research.

Area of Science:

  • Surgical Oncology
  • Minimally Invasive Procedures
  • Lymphedema Management

Background:

  • Minimally invasive inguinal lymph node dissection (MILND) offers benefits like fewer wound complications and shorter hospital stays.
  • Despite advancements, seroma formation is a persistent and significant source of morbidity following MILND.

Purpose of the Study:

  • To determine the incidence of post-operative seroma after MILND.
  • To evaluate the effectiveness of various interventions aimed at reducing seroma formation in these patients.

Main Methods:

  • Retrospective analysis of 44 MILND procedures performed between 2010 and 2017.
  • Examination of patient data to identify risk factors for seroma development.
  • Assessment of multiple interventions trialed to decrease seroma rates.

Main Results:

  • Fifty percent (22/41) of patients developed symptomatic seroma requiring intervention.
  • Risk factors included increased metastatic nodes, higher BMI, older age, and larger drain bulbs.
  • Postoperative seroma was significantly associated with lymphedema.
  • Interventions attempted were unsuccessful in reducing the overall seroma rate.

Conclusions:

  • Seroma formation is a common complication following MILND.
  • Further research is essential to develop effective strategies for reducing seroma incidence in patients undergoing MILND.
Keywords:
Minimally invasive inguinal lymph node dissectionPost-operative complicationSeromaVideoscopic

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