Related Experiment Video
Updated: Jan 22, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Contrast-enhanced swallow study sensitivity for detecting esophagojejunostomy leakage
U Clemente-Gutiérrez1, J G Rodríguez-Chong2, J Morales-Maza1
1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
The contrast-enhanced swallow study showed limited 66% sensitivity for detecting esophagojejunostomy leaks after total gastrectomy. High suspicion is needed for negative studies, suggesting a more comprehensive diagnostic approach for anastomotic leaks.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Diagnostic Imaging
Background:
- Esophagojejunostomy leaks occur in up to 12.3% of total gastrectomy cases for gastric cancer.
- Standardized diagnostic procedures for anastomotic leaks are lacking.
- Early detection of leaks is crucial for patient outcomes.
Purpose of the Study:
- To determine the diagnostic sensitivity of contrast-enhanced swallow studies for detecting esophagojejunostomy leakage.
- To evaluate the effectiveness of imaging in identifying post-gastrectomy complications.
Main Methods:
- Retrospective analysis of patients undergoing total gastrectomy for gastric adenocarcinoma (2002-2017).
- Identification of demographic, clinical, and radiologic factors related to anastomotic leaks.
- Calculation of the sensitivity of contrast-enhanced swallow studies for leak detection.
Main Results:
- 31.01% of 58 patients experienced anastomotic leaks.
- The contrast-enhanced swallow study demonstrated a diagnostic sensitivity of 66% for detecting leaks.
- Gastric adenocarcinoma was the indication for surgery in all cases.
Conclusions:
- The contrast-enhanced swallow study has limited diagnostic efficiency (66% sensitivity) for esophagojejunostomy leaks.
- High clinical suspicion is recommended for patients with initially negative studies.
- A more extensive diagnostic approach may be necessary when leaks are suspected.
Related Concept Videos
Sputum Studies II: Culture and Sensitivity
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Upper GI Series: Barium Swallow
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Urine Studies II: Urine Culture and Sensitivity Test
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Self-Evaluation: Self-Enhancement and Self-Verification
Bioavailability Enhancement: Drug Solubility Enhancement

