Related Experiment Video
Updated: Jan 22, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Voice Characteristics in Patients with Thyroid Disorders
Lejla Junuzović-Žunić1, Amela Ibrahimagić1, Selma Altumbabić2
1Department of Speech and Language Pathology and Audiology, School of Education and Rehabilitation, University of Tuzla, Tuzla, Bosnia and Herzegovina.
Thyroid disorders like hypothyroidism and hyperthyroidism impact voice quality. Drug therapy improved acoustic measures for hypothyroidism, while both groups showed noticeable perceptual voice changes.
Area of Science:
- Endocrinology
- Speech and Language Pathology
Background:
- Thyroid gland disorders, including hypothyroidism and hyperthyroidism, can affect vocal function.
- Assessing voice changes is crucial for understanding the impact of these endocrine conditions.
Purpose of the Study:
- To investigate the acoustic and perceptual voice characteristics in patients with hypothyroidism and hyperthyroidism.
- To evaluate the effects of drug therapy on voice parameters six months after diagnosis.
Main Methods:
- Included 47 female outpatients diagnosed with hypothyroidism or hyperthyroidism.
- Assessed acoustic, perceptual (using the GRBAS scale), and aerodynamic voice parameters before and after drug therapy.
Main Results:
- Hypothyroidism patients showed significant changes in amplitude perturbation, jitter, and noise-to-harmonics ratio post-treatment.
- Hyperthyroidism patients had significant changes in maximum phonation time; both groups exhibited notable perceptual voice deviations.
Conclusions:
- Thyroid disease significantly affects voice quality.
- While acoustic changes may be minor, perceptual voice deviations are prominent in patients with hypothyroidism and hyperthyroidism, even after treatment.
Related Concept Videos
Characteristics of Life
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Intrinsically Disordered Proteins
Characteristics of Fluids
Characteristics of Fluids
Fluids, which include both liquids and gases, are substances that deform continuously under shearing stress. For example, water and oil are liquids with molecules that can...
Characteristics of BJT
For input characteristics, the base-emitter voltage is varied, maintaining a constant collector-emitter voltage. This setup reveals a Shockley-type dependence of the collector current on...

