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FHIRCap: Transforming REDCap forms into FHIR resources.

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This study introduces FHIRCap, a tool transforming REDCap data into FHIR resources for better clinical data sharing. It enables existing clinical trial data to be standardized without form modification.

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Area of Science:

  • Health Informatics
  • Clinical Data Management

Background:

  • Electronic data capture systems like REDCap are common in clinical trials.
  • Current systems lack robust support for clinical data sharing and interoperability.
  • Standardizing clinical data is crucial for research and care.

Purpose of the Study:

  • To implement and assess FHIRCap, a transformation engine mapping REDCap forms to Fast Healthcare Interoperability Resources (FHIR).
  • To evaluate the feasibility of transforming existing REDCap data into FHIR resources.

Main Methods:

  • Development of a transformation engine (FHIRCap) with rule-based mapping.
  • Implementation of a case study using an Australian Genomics project.
  • Analysis of transformation accuracy and identification of form design issues.

Main Results:

  • FHIRCap demonstrated flexibility in mapping most REDCap data to FHIR resources.
  • The system successfully transformed data from a real-world clinical trial.
  • Identified form design issues and provided recommendations for improved transformation.

Conclusions:

  • It is feasible to transform most data in existing REDCap projects to FHIR resources.
  • FHIRCap facilitates the standardization of clinical trial data without altering original forms.
  • This approach significantly enhances the availability of clinical trial data in a standardized format.