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Updated: Jan 22, 2026

Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
Published on: June 7, 2017
Immunological Assays used to Support Efficacy of Zika Virus Vaccines
Kenneth H Eckels1, Rafael A De La Barrera2, Joseph Robert Putnak2
1Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910, USA. kenneth.h.eckels.ctr@mail.mil.
Abstract:
In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discuss published scientific efforts associated with these novel vaccines, emphasizing the immunological assays used to evaluate their immunogenicity and efficacy, and support future licensure.
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