Related Experiment Video
Updated: Jan 22, 2026
08:39
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
5.4K
Precision Medicine in Oncology Pharmacy Practice
Claire Saadeh1, David Bright2, Danielle Rustem3
1Ferris State University College of Pharmacy, Department of Pharmacy Practice; Sparrow Health System Department of Pharmacy; and Herbert-Herman Cancer Center. clairesaadeh@ferris.edu.
Acta Medica Academica
|July 3, 2019
Summary
Precision medicine in oncology optimizes cancer drug therapy by integrating genetic, environmental, and lifestyle factors. Pharmacogenomics (PGx) guides targeted treatments and dosing, minimizing toxicity through interprofessional collaboration.
Area of Science:
- Oncology
- Pharmacogenomics
- Precision Medicine
Background:
- Precision medicine in oncology integrates individual variability in genes, environment, and lifestyle for cancer drug therapy.
- Genomic assays are standard in oncology, with interprofessional teams guiding targeted therapies.
- Pharmacogenomics (PGx) utilizes genetic polymorphisms to refine medication selection and dosing.
Purpose of the Study:
- To review components, processes, and resources for applying precision medicine in cancer drug therapy.
- To emphasize the role of oncology pharmacy practice within precision medicine initiatives.
- To highlight the integration of pharmacogenomics into cancer treatment and supportive care.
Main Methods:
- Review of precision medicine strategies in oncology.
- Examination of pharmacogenomics (PGx) applications in cancer drug therapy.
- Discussion of resources like OncoKB and Clinical Pharmacogenetics Implementation Consortium guidelines.
Main Results:
- Pharmacogenomic-based dosing recommendations exist for several oncolytic and supportive care agents to reduce toxicity.
- Resources such as OncoKB and CPIC provide evidence-based guidance for somatic mutations and PGx.
- Pharmacists play a key role in molecular tumor boards, PGx dosing, and patient education.
Conclusions:
- Precision medicine is a rapidly advancing field in oncology.
- An interprofessional approach involving drug therapy experts is essential for effective precision medicine.
- Pharmacists are integral to implementing precision medicine strategies in oncology pharmacy practice.
Related Concept Videos
03:37Uncertainty in Measurement: Accuracy and Precision
100.3K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.
100.3K
01:52Accuracy and Precision
14.5K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. Highly accurate...
14.5K
01:29Microorganisms in Medicine and Therapeutics
1.0K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.0K
01:16Characteristics of Practical Op Amps
837
A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
837
01:30Theoretical Foundations of Nursing Practice
17.3K
Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
17.3K
01:28Equivalent Circuits for Practical Transformers
1.4K
The practical equivalent circuits of single-phase two-winding transformers exhibit significant deviations from their idealized versions due to the inherent properties of winding resistance and finite core permeability. These properties result in real and reactive power losses, affecting the transformer's performance. Understanding these deviations is crucial for designing more efficient transformers.
In a practical transformer, each winding exhibits resistance and leakage reactance. The...
In a practical transformer, each winding exhibits resistance and leakage reactance. The...
1.4K