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Adequacy of antibiotic prophylaxis protocol in appendectomies in children

Manuel Durán-Poveda1, Pablo Gil-Yonte2, Diego Rodríguez-Villar3

  • 1Departamento de Medicina y Cirugía, Universidad Rey Juan Carlos, Madrid. España.

Cirugia Y Cirujanos
|July 3, 2019
PubMed

Insights

High antibiotic prophylaxis compliance in pediatric appendectomies (90.7%) did not impact surgical site infection rates (2.7%). While compliance was good, timing of administration was the main reason for non-compliance.

Area of Science:

  • Pediatric Surgery
  • Infectious Disease Prevention
  • Surgical Site Infection (SSI) Control

Background:

  • Antibiotic prophylaxis is standard for preventing SSIs in pediatric appendectomies.
  • Assessing compliance and its impact on SSI is crucial for optimizing surgical care.

Purpose of the Study:

  • To evaluate the adherence to antibiotic prophylaxis protocols in children undergoing appendectomy.
  • To determine the relationship between antibiotic prophylaxis compliance and the incidence of surgical site infections.

Main Methods:

  • Prospective cohort study involving 412 pediatric patients undergoing appendectomy.
  • Compliance with antibiotic prophylaxis was assessed, and reasons for non-compliance were identified.
  • Logistic regression analysis was used to determine the effect of compliance on SSI rates.

Main Results:

  • Overall protocol compliance for antibiotic prophylaxis was 90.7%.
  • The primary reason for non-compliance was the timing of antibiotic initiation.
  • The cumulative incidence of surgical site infection was 2.7%, with no statistically significant association found between prophylaxis compliance and SSI (RR: 1.01; p=0.61).

Conclusions:

  • Adherence to antibiotic prophylaxis in pediatric appendectomies is high but has room for improvement.
  • Current compliance levels with antibiotic prophylaxis do not appear to influence the rate of surgical site infections in this population.
Abstract

Keywords:
AdecuaciónAntibiotic prophylaxisComplianceInfección quirúrgicaPediatricsPediatríaProfilaxis antibióticaSurgical wound infection

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