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Characterization of a broad-scope amino acid transport system in sand dollars
J P Davis1, S Bellis, G C Stephens
1Department of Developmental and Cell Biology, University of California, Irvine 92717.
Abstract:
Both echinoderm embryos and adults take up alpha-amino acids by an apparent broad-scope transport system. This transporter can be characterized as follows: alanine transport is not blocked by alpha-(methylamino)isobutyric acid. Leucine and other lipophilic neutral amino acids are preferentially transported. Transport is sodium dependent and blocked by 2-aminobicyclo-[2,2,1]heptane-2-carboxycylic acid. Lysine and aspartate transport is inhibited by lipophilic neutral amino acids. Taurine, a beta-neutral amino acid, is translocated via a second and independent carrier.
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