Related Experiment Video

Updated: Jan 22, 2026

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

30.7K

Late correction of tetralogy of Fallot in children

Paul P Heinisch1, Laetitia Guarino1, Damian Hutter2

  • 1Centre for Congenital Heart Disease, Department of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Swiss Medical Weekly
|July 4, 2019
PubMed

Insights

Late surgical correction of Tetralogy of Fallot (ToF) in children is safe and effective. This study shows excellent early postoperative outcomes, comparable to timely correction, with a high rate of valve-sparing procedures.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Surgery
  • Cardiac Surgery

Background:

  • Tetralogy of Fallot (ToF) is a complex congenital heart defect requiring surgical intervention.
  • Late correction after infancy presents unique challenges and outcomes.
  • Understanding the results of delayed surgical intervention is crucial for patient management.

Purpose of the Study:

  • To evaluate the safety and efficacy of late surgical correction for Tetralogy of Fallot (ToF) in pediatric patients.
  • To analyze surgical techniques and perioperative outcomes in a humanitarian program setting.
  • To compare early postoperative results with those of conventionally timed ToF correction.

Main Methods:

  • Retrospective analysis of 25 children undergoing total surgical correction of ToF after infancy.
  • Data collected on surgical techniques, perioperative parameters, and early outcomes.
  • Short-term (one-month) clinical and echocardiographic follow-up due to program constraints.

Main Results:

  • No major adverse cardiac and cerebrovascular events (MACCE) or in-hospital mortality.
  • Successful valve-sparing pulmonary valve repair in 96% of patients.
  • Significant reduction in mean right ventricular/pulmonary artery (RV/PA) gradient post-surgery.

Conclusions:

  • Late surgical correction of ToF is a safe and viable option.
  • Early postoperative results are comparable to those of timely correction.
  • Valve-sparing techniques are feasible in the majority of patients undergoing late ToF repair.
Abstract

More Related Videos

Studying Brain Function in Children Using Magnetoencephalography08:00

Studying Brain Function in Children Using Magnetoencephalography

Published on: April 8, 2019

9.6K
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

11.2K

Related Concept Videos

Distance Corrections01:15

Distance Corrections

To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
284
Power Factor Correction01:20

Power Factor Correction

The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
505
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
1.0K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
263
Pedigree Analysis01:35

Pedigree Analysis

Overview
89.0K
Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
22.2K