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Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy
Published on: August 15, 2014
Optimization: In-Depth Examination and Proposition
Huy Phuong Phan1, Bing Hiong Ngu1, Alexander Seeshing Yeung2
1School of Education, Faculty of Humanities, Arts, Social Sciences and Education, University of New England, Armidale, NSW, Australia.
Abstract:
One notable concept that is of interest is a person's state of optimal functioning. Achieving optimal functioning (e.g., subjective well-being at school), aside from personal autonomy, requires some form of "optimization." Optimization, we argue, is more than just an "enhancement," a "predictive effect," and/or a "causal flow" between an independent variable (IV) and a dependent variable (DV). We note from existing literature that optimization has often been referred to without a clear, definitive explanation of what this term actually entails. At the same time, we acknowledge that unlike other areas of development (e.g., engagement), no theoretical article is available to explain the concept of optimization. This article considers a number of theoretical tenets for advancement: (1) the tenet of three major criteria that could assist in the explanation, assessment, and measurement of optimization, (2) the tenet of the development of a methodological conceptualization that could measure and assess optimization, and (3) the tenet of the "quantification" of optimization, and in particular, a proposed index of optimization and a corresponding scientific notation of "γ", which we coin as an "optimizing effect." Overall, we contend that this examination is insightful and holistic, seeking clarity into an important topical theme in psychology.
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