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Clinical effects of warmed humidified carbon dioxide insufflation in infants undergoing major laparoscopic surgery

Tong Meng-Meng1, Xu Xue-Jun2, Bao Xiao-Hong2

  • 1Department of Operating Room.

Medicine
|July 7, 2019
PubMed

Insights

Warmed humidified carbon dioxide (CO2) insufflation in infants undergoing laparoscopic surgery helps maintain core body temperature (CBT) and improves postoperative outcomes. This method reduces shivering, hypothermia, and hospital stays, while speeding up bowel movement recovery.

Area of Science:

  • Pediatric Surgery
  • Anesthesiology
  • Laparoscopic Surgery

Background:

  • Studies suggest warmed humidified CO2 insufflation reduces pain and improves core body temperature (CBT) in adult laparoscopic surgery.
  • Limited research exists on its effects in infants undergoing similar procedures.

Purpose of the Study:

  • To investigate the clinical effects of warmed, humidified CO2 insufflation in pediatric patients undergoing major laparoscopic surgeries.
  • To assess the impact on core body temperature and postoperative recovery.

Main Methods:

  • Randomized controlled trial involving infants undergoing major laparoscopic surgery.
  • Comparison between standard CO2 insufflation (Group A) and warmed humidified CO2 (35°C, 95% RH) (Group B).
  • Primary outcome: change in CBT; Secondary outcomes: surgery time, blood loss, oxygen saturation (SO2), and pain scores (FLACC scale).

Main Results:

  • Warmed humidified CO2 group (Group B) showed significantly higher CBT at surgery's end (P=.021).
  • Group B experienced significantly less postoperative shivering (P=.02) and hypothermia (P=.032).
  • Group B demonstrated faster bowel movement recovery (P=.044) and shorter hospital stays (P=.038) without affecting operative time, blood loss, SO2, or pain scores.

Conclusions:

  • Warmed humidified CO2 insufflation is beneficial for maintaining normothermia in infants during major laparoscopic surgery.
  • This technique is associated with improved postoperative outcomes, including reduced shivering and hypothermia, accelerated bowel function recovery, and shorter hospital stays.
Abstract

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