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T2* Mapping Techniques: Iron Overload Assessment and Other Potential Clinical Applications
Katia Menacho1, Amna Abdel-Gadir2, James C Moon3
1Barts Heart Centre, The Cardiovascular Magnetic Resonance Imaging Unit, Institute of Cardiovascular Science, University College London, St Bartholomew's Hospital, 2nd Floor, King George V Block, West Smithfiled, London EC1A 7BE, UK.
Magnetic Resonance Imaging Clinics of North America
|July 8, 2019
Summary
T2* mapping techniques are now reliable for assessing iron overload and other conditions. This article details T2* imaging acquisition, processing, and analysis for clinical use.
Area of Science:
- Medical Imaging
- Cardiovascular MRI
- Biomedical Engineering
Background:
- T2* mapping techniques have advanced significantly since the early 2000s.
- Substantial evidence supports the routine clinical use of T2* mapping for iron overload assessment.
- T2* mapping offers a non-invasive method for evaluating tissue iron concentration.
Purpose of the Study:
- To provide a comprehensive guide on performing T2* imaging.
- To detail the acquisition, postprocessing, and data analysis of T2* mapping.
- To highlight the clinical applications and advancements in T2* mapping techniques.
Main Methods:
- Focus on optimal T2* imaging acquisition protocols.
- Describe standardized postprocessing steps for T2* data.
- Explain methods for analyzing T2* data with clinical correlation.
Main Results:
- T2* mapping is a robust and accurate technique for clinical use.
- Advancements have expanded T2* mapping's utility beyond iron overload.
- Newer techniques improve the reliability and accuracy of T2* measurements.
Conclusions:
- T2* mapping is a well-established tool for iron overload assessment.
- T2* mapping is increasingly valuable for noncontrast ischemia imaging.
- T2* mapping aids in evaluating intramyocardial hemorrhage and microvascular obstruction.
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