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Validation of the Azeri version of the Pediatric Epilepsy Side Effects Questionnaire

Salayev Kamran1, Magalov Sharif2, Garaybayli Garay2

  • 1Azerbaijan Medical University, 100, Mardanov qardaslari str., AZ1078, Baku, Azerbaijan. ksalayev@yahoo.com.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|July 8, 2019
PubMed

Insights

The Azeri version of the Pediatric Epilepsy Side Effects Questionnaire (PESQ) is a reliable tool for assessing antiepileptic drug side effects in children with epilepsy, improving quality of life monitoring.

Area of Science:

  • Pediatric Neurology
  • Clinical Psychology
  • Pharmacology

Background:

  • Long-term antiepileptic drug (AED) use in children with epilepsy can negatively impact quality of life and treatment adherence.
  • Accurate assessment of AED side effects is crucial for managing pediatric epilepsy.
  • Validated instruments are needed to evaluate the impact of AEDs on children's well-being.

Purpose of the Study:

  • To validate the Azeri version of the Pediatric Epilepsy Side Effects Questionnaire (PESQ).
  • To establish the reliability and validity of the PESQ for assessing AED side effects in children with epilepsy.
  • To provide a culturally adapted tool for monitoring AED-related adverse events in Azeri-speaking populations.

Main Methods:

  • The Azeri version of the PESQ was administered to caregivers of 120 children (aged 2-18) with epilepsy.
  • The Strengths and Difficulties Questionnaire (SDQ) was used to screen for comorbid behavioral and emotional problems.
  • Factor analysis, internal consistency assessment, and construct validity analysis were performed on the PESQ data.

Main Results:

  • Principal component analysis confirmed a five-factor structure for the PESQ.
  • The PESQ demonstrated strong internal consistency (Cronbach's alpha = 0.86) for the total side effects scale.
  • Higher PESQ scores were observed in children receiving polytherapy, supporting construct validity. A strong correlation was found between PESQ and SDQ total scores.

Conclusions:

  • The Azeri version of the PESQ is a reliable and valid instrument for assessing AED side effects in children with epilepsy.
  • The PESQ can be utilized across the spectrum of epileptic syndromes.
  • This validated tool aids in monitoring and managing AED side effects, potentially improving patient outcomes.
Abstract

Keywords:
EpilepsyPediatric Epilepsy Side Effects QuestionnaireStrengths and Difficulties Questionnaire

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