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Updated: Jan 22, 2026

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells
Published on: February 18, 2016
[Hepatic adenoma with high phlogosis indices: what relationship? Description of a pediatric clinical case.]
Beatrice Scarpellini1, Martina Mainetti2, Sylvie Tagliati1
1UOC di Pediatria e Neonatologia, Ospedale di Ravenna, AUSL della Romagna - Scuola di Specializzazione in Pediatria, Università di Ferrara.
Abstract:
Hepatocellular adenoma is a benign neoplasm that accounts for 2-4% of pediatric liver tumors. The inflammatory variant of the adenoma can be expressed at the clinical level only with the evidence of persistent elevation of the inflammatory indices, since the hepatic mass is itself silent unless there are complications. The main complications relate to the bleeding risk, the chronic inflammatory state and the low risk of malignant evolution. The predictive marker of hemorrhagic complication is the size and in particular if the diameter is greater than 5 cm surgical treatment is recommended. We describe the case of a 9-year-old girl with a hepatocellular adenoma in the telangiectatic inflammatory variant, with a clinical presentation of loss of appetite and high inflammatory indices.
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