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Estimating kinetic constants in the Michaelis-Menten model from one enzymatic assay using Approximate Bayesian

Jakub M Tomczak1, Ewelina Węglarz-Tomczak2

  • 1Institute of Informatics, Faculty of Science, University of Amsterdam, The Netherlands.

FEBS Letters
|July 9, 2019
PubMed
Summary

This study introduces a new method to calculate enzyme kinetic constants using just one assay, significantly reducing costs and time. This simplifies enzyme kinetics research by minimizing enzyme usage and experimental complexity.

Keywords:
Approximate Bayesian ComputationBayesian statisticsMichaelis-Menten kineticsenzymologylikelihood-free

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