Related Experiment Video
Updated: Jan 22, 2026
10:25
Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury
Published on: August 30, 2011
18.7K
Surviving cardiac arrest from mitral annular disjunction: A case report
Sadie Bennett1, Thanh Phan1, Ashish Patwala1
1Royal Stoke University Hospital, Stoke-on-Trent, UK.
Echocardiography (Mount Kisco, N.Y.)
|July 10, 2019
Summary
A young man survived cardiac arrest due to ventricular fibrillation. Mitral annular disjunction, a previously unrecognized condition, was identified as the likely cause, highlighting its link to sudden cardiac death.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
Background:
- Sudden cardiac death (SCD) and ventricular fibrillation (VF) pose significant health challenges.
- Idiopathic VF is diagnosed when no underlying structural or electrical heart disease is identified.
Observation:
- A 38-year-old man experienced out-of-hospital cardiac arrest due to VF, with initial investigations revealing no significant cardiac abnormalities.
- Despite negative tests for common causes like Brugada syndrome and coronary artery disease, he was diagnosed with idiopathic VF and received an implantable cardioverter-defibrillator.
Findings:
- A subsequent echocardiogram identified mitral annular disjunction (MAD), a condition increasingly recognized for its association with life-threatening arrhythmias.
- MAD involves a separation between the mitral valve annulus and the left ventricular myocardium.
Implications:
- This case underscores the importance of considering MAD in patients presenting with unexplained ventricular fibrillation and sudden cardiac arrest.
- Increased awareness and diagnostic focus on MAD may improve risk stratification and management strategies for patients at risk of SCD.
Keywords:
cardiac magnetic resonance imagingechocardiographymitral annular disjunctionmyxomatous mitral valvesudden cardiac arrestMore Related Videos
08:19Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
Published on: July 12, 2022
3.4K
07:02Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest
Published on: January 5, 2018
12.5K
Related Concept Videos
01:22Mitral Stenosis I: Introduction
514
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
514
01:19Survival Tree
393
Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
Building a Survival Tree
Constructing a...
Building a Survival Tree
Constructing a...
393
01:18Survival Curves
669
Survival curves are graphical representations that depict the survival experience of a population over time, offering an intuitive way to track the proportion of individuals who remain event-free at each time point. These curves are widely used in fields such as medicine, public health, and reliability engineering to visualize and compare survival probabilities across different groups or conditions.
The Kaplan-Meier estimator is the most common method for constructing survival curves. This...
The Kaplan-Meier estimator is the most common method for constructing survival curves. This...
669
01:20Mitral Regurgitation I: Introduction
449
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
449
01:27Mitral Valve Prolapse I: Introduction
416
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
416
01:18Introduction To Survival Analysis
763
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time...
The primary goal of survival analysis is to estimate survival time—the time...
763