[Develop the active surveillance system for vaccine safety in China]

Area of Science:

• Public Health
• Vaccinology
• Epidemiology

Background:

• Post-marketing vaccine safety surveillance is crucial for public health.
• Current passive surveillance systems in China suffer from under-reporting and incompleteness.
• Active surveillance offers a more robust alternative to passive systems.

Purpose of the Study:

• To highlight the need for an active vaccine safety surveillance system in China.
• To propose suggestions for establishing such a system, considering China's specific context.
• To leverage global experiences in active surveillance.

Main Methods:

• Scoping review of international literature on active vaccine safety surveillance.
• Analysis of the current vaccine safety surveillance landscape in China.
• Development of recommendations tailored to China's situation.

Main Results:

• Passive surveillance in China faces significant limitations.
• Active surveillance systems have demonstrated effectiveness in developed countries.
• A tailored active surveillance system is feasible and necessary for China.

Conclusions:

• Establishing an active surveillance system for vaccine safety in China is imperative.
• Learning from global best practices is essential for successful implementation.
• Proactive development of active surveillance will enhance vaccine safety and public health protection in China.