Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colloids03:22

Colloids

20.8K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
20.8K
Polymers02:34

Polymers

40.5K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
40.5K
Polymers02:34

Polymers

23.2K
23.2K
Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

386
The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
386
Colloids and Suspensions01:17

Colloids and Suspensions

3.2K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
3.2K
Colloidal precipitates01:09

Colloidal precipitates

5.9K
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structure and stability of styrene-maleic acid lipid particles: the role of polymer-lipid ratio.

Journal of colloid and interface science·2026
Same author

Self-Recoverable, Energy-Dissipating, and Healable Chain-Extended Supramolecular Polyurethanes and Poly(urethane-urea)s for Impact-Resistant Systems.

ACS applied materials & interfaces·2026
Same author

Unlocking complete sugarcane residue valorisation for sequential fractionation of cellulose, hemicellulose and lignin through a one-pot, two-step deep eutectic solvent strategy.

Carbohydrate polymers·2026
Same author

Sparingly PEGylated Adipate Copolymers via Enzymatic Synthesis as Nano-Carriers for Solid Dispersions.

Biomacromolecules·2026
Same author

Core-block engineering enables control of ice recrystallisation inhibition in polymer nanoparticles.

Chemical science·2026
Same author

Supramolecular Near-Infrared Photocatalysts for Efficient and Oxygen-Tolerant Aqueous RAFT Polymerization.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jan 22, 2026

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

8.0K

Refractive index matched, nearly hard polymer colloids.

Gregory N Smith1, Matthew J Derry1, James E Hallett2

  • 1Department of Chemistry, University of Sheffield, Brook Hill, Sheffield S3 7HF, UK.

Proceedings. Mathematical, Physical, and Engineering Sciences
|July 12, 2019
PubMed
Summary
This summary is machine-generated.

Researchers developed new transparent, refractive index matched colloidal particles using polymerization-induced self-assembly (PISA). These particles avoid issues like swelling and charging, offering a promising model system for colloid science studies.

Keywords:
X-ray scatteringcolloidslight scatteringtransparent dispersions

More Related Videos

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
10:56

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Published on: May 20, 2014

12.5K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.4K

Related Experiment Videos

Last Updated: Jan 22, 2026

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

8.0K
Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
10:56

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Published on: May 20, 2014

12.5K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

10.4K

Area of Science:

  • Colloid and Surface Science
  • Polymer Chemistry
  • Materials Science

Background:

  • Refractive index matched particles are crucial for studying colloidal systems, often using poly(methyl methacrylate) latexes.
  • Dispersing latexes in mixed solvents can cause particle charging or swelling, limiting their utility.
  • Alternative methods are needed to create well-defined, refractive index matched colloidal spheres.

Purpose of the Study:

  • To synthesize novel refractive index matched colloidal nanoparticles using polymerization-induced self-assembly (PISA).
  • To overcome limitations associated with traditional refractive index matching techniques for colloidal spheres.
  • To establish a new model system for exploring colloidal structure and dynamics.

Main Methods:

  • Synthesized poly(stearyl methacrylate)-poly(2,2,2-trifluoroethyl methacrylate) (PSMA-PTFEMA) diblock copolymers via PISA.
  • Utilized *n*-alkanes as solvents, identifying *n*-tetradecane for optimal refractive index matching.
  • Controlled nanoparticle size by adjusting the degree of polymerization of the PTFEMA block.
  • Characterized concentrated dispersions and measured nanoparticle diffusion dynamics.

Main Results:

  • Successfully created refractive index matched diblock copolymer nanoparticles with PTFEMA cores in *n*-alkanes.
  • *n*-Tetradecane was identified as the optimal solvent for refractive index matching.
  • Nanoparticle diameter was tunable by controlling the PTFEMA block length.
  • Diffusion measurements demonstrated the potential of these nanoparticles as model systems.

Conclusions:

  • PSMA-PTFEMA diblock copolymer nanoparticles synthesized via PISA offer a superior alternative to traditional latexes for refractive index matching.
  • This new system provides transparent spheres in a single, non-ionizable solvent, avoiding common issues.
  • These nanoparticles represent a promising platform for advanced colloidal research.