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Updated: Jan 22, 2026

Characterization and Application of Passive Samplers for Monitoring of Pesticides in Water
Published on: August 3, 2016
Genetic polymorphisms as determinants of pesticide toxicity: Recent advances
Michele Teodoro1, Giusi Briguglio1, Concettina Fenga1
1Department of Biomedical and Dental Sciences and Morphofunctional Imaging - Occupational Medicine Section - University of Messina, Italy.
Abstract:
Occupational and environmental exposure to pesticides may induce harmful effects on human health by promoting the development of a wide range of disorders. Some of the most recently hypothesized mechanisms are oxidative stress and epigenetic modifications, however biological effects seem to be modulated mainly by the occurrence of genetic polymorphisms. The susceptibility to exposure can be evaluated by studying the most common polymorphisms of genes involved in the metabolism of organophosphorus compounds (cytochrome P450, glutathione transferase, acetyltransferases or paraoxonase 1). The aim of this article is to review recent literature data concerning the influence of genetic polymorphisms on pesticides-induced oxidative damage.
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