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Erythroderma and Chronic Lichenification Due to Metformin
Javier Moreno Díaz1, Jose Miguel García Bruñén1, Rocío Bermúdez Cameo2
1Internal Medicine Department, University Hospital Miguel Servet, Zaragoza, Spain.
European Journal of Case Reports in Internal Medicine
|July 12, 2019
Summary
Metformin, a common diabetes medication, can cause erythroderma, a severe skin condition. This case highlights the importance of considering drug-induced reactions in persistent skin issues.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Pruritus and erythroderma are significant dermatological conditions.
- Metformin is a widely prescribed medication for type 2 diabetes.
Purpose of the Study:
- To report a case of erythroderma secondary to metformin use.
- To emphasize the importance of considering drug-induced causes for erythroderma.
Main Methods:
- Case presentation of a 62-year-old male patient.
- Exclusion of other potential causes of erythroderma (contact allergies, toxic products, autoimmune diseases).
- Diagnosis confirmed by skin biopsy.
Main Results:
- The patient presented with a 4-year history of pruritus and erythroderma.
- Erythroderma was attributed to metformin use.
- Skin biopsy confirmed the diagnosis and showed lichenification.
Conclusions:
- Drug-induced erythroderma, even from common medications like metformin, must be considered.
- Thorough clinical evaluation, including history and skin biopsy, is crucial for diagnosing erythroderma.
- Prompt treatment of erythroderma is essential once the underlying cause is identified.
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