Related Experiment Video
Updated: Jan 22, 2026

Porcine As a Training Module for Head and Neck Microvascular Reconstruction
Published on: September 29, 2018
Osteoradionecrosis, an increasing indication for microvascular head and neck reconstruction
D Danielsson1, C Gahm2, S Haghdoost3
1Department of Clinical Science, Intervention and Technology, Division of Ear, Nose and Throat Diseases, Karolinska Institute, Stockholm, Sweden; Patient Area Craniofacial Diseases, Karolinska University Hospital, Stockholm, Sweden.
Osteoradionecrosis (ORN) reconstruction using free flaps is increasing among cancer survivors. This trend highlights the need for adequate healthcare resources to manage late adverse effects of cancer treatment.
Area of Science:
- Oncology
- Head and Neck Surgery
- Plastic Surgery
Background:
- Cancer survivorship is increasing due to improved treatments.
- Survivors often experience late adverse effects from cancer therapy.
- Osteoradionecrosis (ORN) is a significant late complication requiring surgical intervention.
Purpose of the Study:
- To determine if free flap reconstructions for ORN have increased over time.
- To compare outcomes between ORN reconstructions and head and neck cancer reconstructions.
Main Methods:
- Retrospective review of head and neck free flap reconstructions.
- Data collected over an 18-year period (1995-2012) at Karolinska University Hospital.
- 235 free flaps analyzed, divided into cancer and ORN groups.
Main Results:
- ORN cases demonstrated longer survival and higher rates of late complications.
- The proportion of free flaps for ORN increased significantly over the study period.
- ORN indications rose from 7.0% (1995-2000) to 27.3% (2007-2012).
Conclusions:
- ORN is an increasing indication for head and neck free flap reconstruction.
- This trend necessitates careful resource allocation in healthcare systems.
- Effective management of cancer survivors with ORN is crucial.
Related Concept Videos
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Indicators
Muscles of the Anterior Neck
Muscles that Move the Head
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
Increased Body Temperature

