Related Experiment Video
Updated: Jan 22, 2026
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
Published on: January 29, 2014
Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process
A Francois Trappey1, Kyle M Thompson, Nathan Kuppermann
1From the David Grant Air Force Medical Center (A.F.T.), Travis Air Force Base, Fairfield, California; Division of Trauma and Acute Care Surgery (A.F.T.), General Surgery Residency Program (K.M.T.), Department of Surgery, Emergency Medicine and Pediatrics (N.K.), UC Davis Health System, Division of Pediatric General and Thoracic Surgery (J.T.S.), Division of Public Health Sciences (M.A.N.), University of California at Davis, Davis, California; Division of Pediatric Emergency Medicine (H.A.H.), Primary Children's Hospital, University of Utah Health, Salt Lake City, Utah; Department of Emergency Medicine (S.R.M.), Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania; Emergency Medicine (R.M.S.), Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, Ohio; Department of Emergency Medicine, Trauma, Acute Care Surgery and Surgical Critical Care (J.M.G.), and Division of Emergency Medicine (D.K.N.), University of California at Davis, Davis, California.
Consensus-based transfusion guidelines were developed for pediatric trauma patients to standardize care. These guidelines aim to reduce variability in transfusion practices for children with hemorrhagic injuries in clinical trials.
Area of Science:
- Pediatric Trauma Care
- Clinical Trial Standardization
- Hemorrhagic Injury Management
Background:
- Significant variability exists in pediatric transfusion practices for hemorrhagic injuries.
- Standardizing transfusion protocols is crucial for multicenter pediatric trauma clinical trials.
- A consensus-based approach was needed to develop guidelines for an upcoming trial on tranexamic acid in children.
Purpose of the Study:
- To develop consensus-based transfusion guidelines for pediatric trauma patients.
- To minimize confounding factors in a multicenter randomized clinical trial.
- To standardize transfusion practices across participating trauma centers.
Main Methods:
- A modified Delphi process was employed with a multidisciplinary expert panel.
- A survey assessed 23 categories of transfusion practices using a 5-point Likert scale.
- Consensus was defined as ≥80% agreement; four survey iterations were conducted.
Main Results:
- 35 panelists from four pediatric trauma centers participated.
- 176 statements were rated across 23 categories.
- 39 statements were accepted, forming the basis for transfusion guidelines and an algorithm.
Conclusions:
- Consensus-based transfusion guidelines were successfully developed for pediatric hemorrhagic injuries.
- These guidelines will help standardize practices in a clinical trial evaluating tranexamic acid.
- Broad interdisciplinary participation ensured comprehensive guideline development.
Related Concept Videos
01:15Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
02:45Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
01:26Guidelines for Nursing Documentation II
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.
01:06Legal Guidelines for Documentation
01:23Guidelines for Sketching a Curve
01:11Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...