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Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
939
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

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Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
287
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

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Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
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Updated: Jan 22, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
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DRESS Syndrome.

Priyansh Jain1, Sneha Garg1, Vinod Kumar Sharma1

  • 1Resident,Department of Medicine, JLN Medical College, Ajmer, Rajasthan.

The Journal of the Association of Physicians of India
|July 14, 2019
PubMed
Summary
This summary is machine-generated.

Carbamazepine can cause Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, a severe adverse drug reaction. This case highlights DRESS syndrome with liver injury possibly induced by carbamazepine.

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Area of Science:

  • Pharmacovigilance
  • Clinical Toxicology
  • Dermatology

Background:

  • Carbamazepine is a widely prescribed antiepileptic and mood-stabilizing drug.
  • Adverse drug reactions (ADRs) to carbamazepine can manifest with diverse clinical presentations.
  • Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a severe, potentially fatal ADR with a characteristic symptom complex.

Observation:

  • A patient developed DRESS syndrome with significant liver injury.
  • The clinical presentation included fever, rash, and systemic involvement.
  • The RegiSCAR scoring system classified the case as "definite" for DRESS syndrome.

Findings:

  • The patient's DRESS syndrome was possibly induced by carbamazepine.
  • Key features included eosinophilia, atypical lymphocytosis, and internal organ involvement (hepatitis).
  • The latency period from drug exposure to symptom onset was notable.

Implications:

  • This case underscores the importance of recognizing carbamazepine-induced DRESS syndrome.
  • Prompt identification and drug withdrawal are crucial for managing DRESS syndrome.
  • Awareness of DRESS syndrome is vital for clinicians managing patients on carbamazepine.