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Effective delivery of palliative radiotherapy: A prospective study
A Clément-Zhao1, M Luu2, J-E Bibault3
1Department of radiotherapy, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France; Department of radiotherapy, institut Curie, 35 rue Dailly, 92210 Saint-Cloud, France.
Summary
Palliative radiotherapy was effectively delivered in most cases, achieving symptom palliation for 68.8% of patients. This study highlights radiation therapy
Area of Science:
- Oncology
- Radiation Oncology
- Palliative Care
Background:
- Palliative radiotherapy aims to alleviate patient discomfort.
- Treatment effectiveness can be limited by rapid deterioration of patient condition.
- Assessing the actual delivery of palliative radiotherapy is crucial.
Purpose of the Study:
- To evaluate the effective delivery of palliative radiotherapy.
- To analyze treatment adherence to initial prescriptions (dose, time, fractionation).
- To assess clinical benefit, treatment interruptions, and patient outcomes.
Main Methods:
- Prospective monocentric study including patients receiving palliative radiotherapy.
- Data collected from December 2015 to February 2016.
- Primary endpoint: effective radiotherapy delivery; Secondary endpoints: treatment breaks, clinical benefit, mortality, palliative care unit admission.
Main Results:
- 64 treatments were analyzed in 59 patients; bone and brain were primary sites.
- Palliative radiotherapy was achieved in 89% of cases, with symptom palliation in 68.8%.
- Treatment interruptions occurred in 9.4%, mainly due to worsening performance status.
Conclusions:
- Palliative radiotherapy was completed as planned in 79.9% of cases, yielding clinical benefit for 68.8%.
- Radiation therapy is a valuable palliative treatment option for end-of-life care.
- Further research should focus on optimizing delivery and patient selection.
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