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Updated: Jan 22, 2026
05:20
A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
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CASE SERIES OF HYPERBARIC OXYGEN THERAPY FOR CENTRAL RETINAL ARTERY OCCLUSION
Thomas C Masters1, Bjorn C Westgard1, Stephen M Hendriksen1
1Department of Emergency Medicine, Division of Hyperbaric Medicine.
Retinal Cases & Brief Reports
|July 16, 2019
Summary
Hyperbaric oxygen (HBO) therapy improved vision in 72% of central retinal artery occlusion patients. Early treatment within 12 hours yielded the best visual acuity outcomes.
Area of Science:
- Ophthalmology
- Hyperbaric Medicine
Background:
- Central retinal artery occlusion (CRAO) is a medical emergency with limited treatment options.
- Hyperbaric oxygen (HBO) therapy involves breathing pure oxygen in a pressurized chamber.
Observation:
- A retrospective chart review analyzed 39 patients with CRAO treated with HBO.
- Patients received 10 HBO treatments over 5 days during their inpatient stay.
Findings:
- 72% of patients experienced improved visual acuity after HBO therapy.
- A mean improvement of 5.05 lines on a modified Snellen chart was observed.
- Treatment within 12 hours of symptom onset resulted in a mean improvement of 6.11 lines.
Implications:
- Emergent HBO therapy is a viable treatment for central retinal artery occlusion.
- HBO therapy was well-tolerated with minor complications like middle ear barotrauma.
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