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Related Experiment Video

Updated: Jan 22, 2026

Mongolian Gerbils as an Animal Model of Wound Healing
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Phototherapeutic keratectomy.

Ritu Nagpal1, Prafulla K Maharana1, Prakhyat Roop1

  • 1Cornea, Cataract and Refractive Surgery Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Survey of Ophthalmology
|July 16, 2019
PubMed
Summary

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This summary is machine-generated.

Phototherapeutic keratectomy (PTK) uses an excimer laser to treat corneal stromal issues, improving clarity. Repeat procedures are possible, and adjunctive treatments can manage recurrences and haze.

Area of Science:

  • Ophthalmology
  • Surgical Procedures
  • Corneal Diseases

Background:

  • Phototherapeutic keratectomy (PTK) is a common excimer laser surgery for anterior corneal stromal pathologies.
  • It ablates corneal stroma to enhance clarity and surface smoothness.

Purpose of the Study:

  • To review the efficacy and considerations of phototherapeutic keratectomy.
  • To highlight its role in managing corneal pathologies and its advantages in resource-limited settings.

Main Methods:

  • Excimer laser ablation of the corneal stroma.
  • Use of adjunctive topical mitomycin-C to reduce recurrence.
  • Application of masking agents for irregular corneal surfaces.

Main Results:

Keywords:
Salzmann nodular degenerationalternatives to keratoplastykeratoconus nodulesphototherapeutic keratectomyrecurrent corneal erosionsspheroidal degeneration

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  • Immediate concerns include transient discomfort and hyperopia.
  • Long-term issues can involve pathology recurrence and corneal haze.
  • Repeat ablations are feasible if corneal thickness allows, without compromising future keratoplasty.
  • Adjunctive therapies can mitigate recurrence and improve outcomes.

    • Conclusions:

    • Phototherapeutic keratectomy is a valuable tool for corneal surgeons.
    • It offers a viable treatment option, especially where donor tissue is scarce.
    • Repeat treatments and adjunctive therapies enhance its utility in managing corneal stromal diseases.