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Published on: July 22, 2014
Abbreviated breast MRI combining FAST protocol and high temporal resolution (HTR) dynamic contrast enhanced (DCE)
Audrey Milon1, Saskia Vande Perre1, Julie Poujol1
1AP-HP, Hôpital Tenon, Department of Radiology, 4 rue de la Chine, 75020, Paris, France.
Adding a high temporal resolution (HTR) dynamic contrast enhanced (DCE) sequence to a FAST MRI protocol improves breast lesion detection and characterization. This enhanced FAST protocol achieves diagnostic performance similar to the full protocol but with a significantly reduced acquisition time.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Breast MRI protocols aim for accurate lesion detection and characterization.
- Standard MRI protocols can be time-consuming.
- The FAST (Functional, Anatomical, and Symptomatic) protocol is a streamlined approach.
Purpose of the Study:
- To evaluate the diagnostic value of adding a high temporal resolution (HTR) dynamic contrast-enhanced (DCE) sequence to a FAST MRI protocol.
- To assess if this combined approach improves diagnostic performance compared to standard protocols.
- To determine if the enhanced protocol can reduce overall MRI acquisition time.
Main Methods:
- Retrospective analysis of 120 women (179 lesions) who underwent breast MRI with subsequent biopsy.
- Lesions were classified using the Breast Imaging-Reporting and Data System (BI-RADS) by two readers.
- Comparison of a FAST protocol, a FULL standard protocol, and an Abbreviated protocol incorporating the HTR-DCE sequence.
Main Results:
- All lesions were visible with the FAST protocol; 95.5% were detected with the HTR-DCE sequence.
- Early enhancement on HTR-DCE (Time To Enhancement < 31s) was significantly associated with malignancy (OR 5.6).
- The enhanced FAST protocol (FAST + HTR-DCE) improved lesion characterization (diagnostic gain of 10.6%) and reduced acquisition time (7 min 48 s vs. 13 min 54 s).
Conclusions:
- Adding an HTR-DCE sequence to a FAST protocol enhances diagnostic performance in breast MRI.
- This approach achieves diagnostic accuracy comparable to the FULL protocol.
- The combined protocol offers a significant reduction in examination time, improving efficiency.
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