Risk Prediction Tools Available for Germline BRCA1/2 Mutations Underperform in Prostate Cancer Patients

Lucía Oliva1, Rebeca Lozano2, Casilda Llácer1

  • 1UGCI Oncología Médica, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga, Spain; CNIO-IBIMA Genitourinary Cancer Research Unit, Institute of Biomedical Research in Malaga, Málaga, Spain.

Summary

Predictive models for BRCA1/2 mutations underperform in prostate cancer (PC) patients. These tools should not guide genetic testing in men with PC, as they miss many mutation carriers.

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