IMPACT India: Insights for Insulin Therapy in Routine Clinical Practice.

Area of Science:

• Endocrinology
• Diabetes Management
• Clinical Pharmacy

Background:

• Insulin therapy is crucial for diabetes management.
• Physician and patient preferences significantly influence insulin regimen selection.
• The IMPACT survey aimed to understand these influences in India.

Purpose of the Study:

• To assess factors influencing the choice of insulin therapy among Indian physicians.
• To identify preferred insulin regimens based on patient characteristics and clinical situations.

Main Methods:

• A questionnaire-based survey was administered to 314 physicians (51% general physicians, 37% diabetologists).
• Physicians reported preferred insulin regimens for various patient profiles, life stages, comorbidities, and lifestyle factors using case scenarios.

Main Results:

• Premix insulin twice daily was preferred for adults (59%) and elderly (53%).
• Basal bolus therapy was favored for pregnant women (>47%) and acute illness (62%).
• Regimen choice varied based on dietary patterns, meal timings, and glucose excursion profiles.

Conclusions:

• Indian physicians demonstrate a logical approach to insulin regimen selection.
• Choices are guided by patient-specific factors such as glucophenotype, diet, psychosocial needs, and comorbidities.