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Magnetic Resonance Imaging in Pediatric Migraine

Megan E Webb1,2,3, Farnaz Amoozegar3,4, Ashley D Harris1,2,3

  • 1Department of Radiology, University of Calgary, Calgary, Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|July 17, 2019
PubMed

Insights

Magnetic resonance imaging (MRI) research in pediatric migraine reveals key differences and similarities compared to adult migraine. This review highlights areas for future research and potential interventions in pediatric migraine.

Area of Science:

  • Neurology
  • Radiology
  • Pediatrics

Background:

  • Migraine is a common neurological disorder affecting both children and adults.
  • Understanding the differences in pediatric migraine is crucial for effective diagnosis and treatment.
  • Magnetic resonance imaging (MRI) offers valuable insights into brain structure and function in migraine.

Purpose of the Study:

  • To review and compare MRI findings in pediatric migraine with adult migraine literature.
  • To identify differences and similarities in clinical and physiological aspects of pediatric versus adult migraine.
  • To pinpoint research gaps and potential intervention targets for pediatric migraine.

Main Methods:

  • Comprehensive literature search of PubMed up to February 2019.
  • Analysis of structural MRI studies (white matter and gray matter).
  • Review of cerebral perfusion, metabolite, and functional MRI (fMRI) studies (task-based and resting-state BOLD).

Main Results:

  • Comparison of pediatric and adult migraine using various MRI techniques.
  • Identification of distinct and shared characteristics between pediatric and adult migraine.
  • Synthesis of data from structural, perfusion, metabolite, and functional imaging studies.

Conclusions:

  • MRI findings underscore the unique aspects of pediatric migraine compared to adult migraine.
  • The review identifies critical areas requiring further investigation in pediatric migraine research.
  • Potential avenues for therapeutic interventions in pediatric migraine are suggested based on imaging data.
Keywords:
Magnetic resonance imagingMagnetic resonance spectroscopyMigrainePediatrics

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