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Relationship between SYNTAX score and myocardial viability in ischemic cardiomyopathy
Semi Öztürk1, Ahmet Seyfeddin Gürbüz2, Cevat Kırma3
1Department of Cardiology, Haseki Training and Research Hospital, İstanbul, Turkey.
Summary
High SYNTAX scores (SS) indicate complex coronary artery disease and are linked to non-viable myocardium in ischemic cardiomyopathy (IC) patients. This complexity predicts poor heart muscle function.
Area of Science:
- Cardiology
- Nuclear Cardiology
- Interventional Cardiology
Background:
- The SYNTAX score (SS) quantifies coronary artery disease complexity.
- Assessing myocardial viability is crucial in ischemic cardiomyopathy (IC).
Purpose of the Study:
- To investigate the association between the SYNTAX score (SS) and myocardial viability/non-viability.
- To evaluate the predictive value of SS for non-viable myocardium in IC patients using positron emission tomography (PET).
Main Methods:
- 107 IC patients undergoing PET were analyzed.
- Patients were categorized based on myocardial viability.
- SS was calculated from coronary angiograms.
Main Results:
- Patients with non-viable myocardium exhibited significantly higher SS (17.6±3.7) compared to those with viable myocardium (14.1±5.2).
- Higher SS was mildly correlated with myocardial non-viability (rpb=-0.28, p=0.004).
- SS was the sole independent predictor of myocardial non-viability (OR: 1.164, p=0.006), with a cutoff of 16 for prediction.
Conclusions:
- A high SYNTAX score is associated with non-viable myocardium in IC patients.
- SS serves as a valuable predictor of myocardial non-viability in this population.
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