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Engineered Vascularized Muscle Flap
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Comparison between Rescue Flap and Double Flap Technique.

Murat Benzer1, Huseyin Biceroglu2, Murat Samet Ates1

  • 1Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey.

Journal of Neurological Surgery. Part B, Skull Base
|July 19, 2019
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Summary
This summary is machine-generated.

Endoscopic pituitary surgery can cause posterior septal perforation, leading to worse breathing and more crusting. Reconstructing the septum reduces these negative effects, improving patient outcomes.

Keywords:
double nasoseptal flapendoscopic approachmorbiditypituitaryrescue flapseptal perforationvisual analog scale

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Surgical Innovation

Background:

  • Endoscopic pituitary surgery often results in mucosal loss in the nasal cavity, specifically the sphenoethmoidal recess and posterior nasal septum.
  • A gap exists in comparative literature regarding primary septal perforation reconstruction versus secondary healing following such procedures.

Purpose of the Study:

  • To evaluate and compare postoperative patient morbidity after endoscopic endonasal pituitary surgery.
  • To assess the outcomes of two reconstruction techniques: rescue flaps and double nasoseptal flaps, in patients with or without posterior septal perforation.

Main Methods:

  • A prospectively randomized study was conducted with sixty participants at a tertiary academic center.
  • Outcomes measured included functional breathing via visual analog scale (VAS), sphenoid sinusitis, synechia formation, posterior septal perforation presence, and sphenoethmoidal recess crusting.

Main Results:

  • Both intact and perforated septum groups showed significant pre- to postoperative changes in VAS scores, with a more pronounced worsening in the posterior septal perforation group.
  • The posterior septal perforation group experienced significantly more crusting compared to the intact septum group.
  • While both groups had worsened VAS scores, the perforated group's decline was substantially greater.

Conclusions:

  • This study is the first to compare postoperative morbidity in endoscopic endonasal pituitary surgery concerning posterior septal perforation.
  • Reconstruction of the posterior septum, coupled with minimized mucosal loss, is associated with improved postoperative nasal symptom scores.
  • The findings suggest that proactive septal reconstruction positively impacts patient recovery and functional outcomes.