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Updated: Jan 22, 2026

Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
Published on: March 12, 2019
[Current criteria for the diagnosis of adrenocortical carcinoma]
L S Selivanova1, A A Roslyakova1, Yu A Kovalenko2
1National Medical Research Center of Endocrinology, Ministry of Health of Russia, Moscow, Russia.
Abstract:
Adrenocortical carcinoma is a rare malignant tumor of the adrenal cortex with an unfavorable prognosis. In 2017, the International Agency for Research on Cancer (IARC) and the World Health Organization (WHO) published the 4th edition of the WHO Classification of Tumors of Endocrine Organs. The updated classification reflects a multidisciplinary experience in diagnosing and predicting the course of adrenal cortex tumors, obtained on the basis of current studies. This paper highlights the key provisions of the updated WHO classification for adrenocortical carcinoma.
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