Related Experiment Video
Updated: Jan 22, 2026

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
Published on: July 10, 2017
Prospective comparison of a nonmodified and a modified mite extract for immunotherapy in children and adolescents
Desireé Hartmann1, Anna Fischl1, Eva Herrmann2
1Department for Children & Adolescents, Division of Allergology, Pulmonology & Cystic fibrosis, Goethe University, 60590 Frankfurt am Main, Germany.
Abstract:
Aim: This prospective study compares nonmodified and modified house dust mite extracts for allergen immunotherapy (AIT) in pediatric patients with allergic asthma. Materials & methods: Total 95 patients underwent bronchial allergen provocation (BAP). AIT was recommended to 62 patients. Complete datasets of 54 subjects were obtained. Primary aim was the comparison of treatment success defined by BAP between two extracts after 1 year. Secondary parameters were laboratory parameters and clinical symptoms. Results: Significant improvement (p < 0.001) was measured by BAP in both treatment groups. No change was seen in the controls. Both extracts exerted comparable effects on all parameters. Conclusion: After 1 year of AIT, the extracts were equally efficient, with significant improvements in 70.0% (nonmodified) and 72.2% (modified) of patients.
More Related Videos
Related Concept Videos
Tumor Immunotherapy
Cognitive Development During Adolescence
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Revisionist Views of Adolescent and Adult Cognition
Erikson's Theory on Socioemotional Development during Adolescence
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...

