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O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression

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Partial Thromboplastin Time: Accurate Measurement Through Evidence-Based Practice.

Summer Drummond¹, Gloria Gotskie², Darlene Landi²

¹University of Pittsburgh Medical Center.

Clinical Journal of Oncology Nursing

|July 20, 2019

Summary

Elevated partial thromboplastin time (PTT) results from implantable ports were inaccurate. Peripheral venipuncture is recommended for reliable coagulation testing, improving patient safety and diagnostic accuracy.

Keywords:

blood draw coagulation panel implantable port partial thromboplastin time venipuncture

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Area of Science:

Clinical Laboratory Science
Hematology
Patient Safety

Background:

Critically elevated partial thromboplastin time (PTT) results were repeatedly observed at a major cancer center.
These inaccurate results were specifically linked to blood samples drawn via central venous access devices, such as implantable ports.

Purpose of the Study:

To investigate the cause of inaccurate PTT results obtained from implantable ports.
To evaluate the efficacy of peripheral venipuncture for coagulation testing compared to central venous access devices.

Main Methods:

A root cause analysis was performed to identify factors contributing to inaccurate PTT results.
The evidence-based practice council reviewed peer-reviewed literature and case studies on blood collection methods for coagulation panels.
Institutional policies and staff education regarding blood collection techniques were assessed.

Main Results:

The analysis indicated that institutional policies and staff education did not adequately support peripheral venipuncture for coagulation panels.
Literature review and case studies confirmed that PTT levels drawn through implantable ports can yield inaccurate results.
Peripheral venipuncture emerged as a potentially more reliable method for obtaining accurate PTT measurements.

Conclusions:

Blood collection via implantable ports can lead to falsely elevated PTT results.
Peripheral venipuncture is a preferable method for accurate PTT testing in clinical practice.
Updating institutional policies and enhancing staff education on proper blood collection techniques are crucial for patient safety and reliable laboratory diagnostics.