Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

627
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
627
Regulation of Food Intake01:30

Regulation of Food Intake

2.3K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
2.3K
Precipitation Titration: Endpoint Detection Methods01:19

Precipitation Titration: Endpoint Detection Methods

5.8K
In argentometric precipitation titrations, endpoints can be detected visually by the Mohr, Volhard, and Fajans methods. In the Mohr method, adding a soluble chromate indicator gives an initial yellow color to the analyte solution. As the titrant is added, the first excess of silver ions forms a red silver chromate precipitate, marking the endpoint. The solution pH should be maintained at about 8 by adding solid CaCO3.
In the Volhard method, a standard excess of AgNO3 is first added to the...
5.8K
Microorganisms in Agriculture and Food industry01:27

Microorganisms in Agriculture and Food industry

1.4K
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
1.4K
Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

Pharmacokinetics: Drug–Food and Drug–Viral Interactions

222
A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
222
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Metabolomics and Proteomics Reveal Gender-Dependent Immunotoxicity Mechanisms of Mineral Oil Saturated Hydrocarbons in Fischer 344 Rats.

Journal of agricultural and food chemistry·2026
Same author

Gallic Acid Improves the Emulsion Capacity of Pectin-Whey Protein Nanofiber Complexes by Altering the Mode of Fiber Entanglement.

Journal of agricultural and food chemistry·2025
Same author

Formation Patterns, In Vivo Toxic Effects, and Metabolomic Conditions of Oxidative Derivatives of Triolein.

Journal of agricultural and food chemistry·2025
Same author

Integrated Metabolomic and Transcriptomic Analyses of Mouse Liver Reveals the In Vivo Toxicity and Mechanisms of Individual and Combined Toxicants Formed in the Thermal Processing of High-Fat Diets.

Journal of agricultural and food chemistry·2025
Same author

Chemometric techniques for the prediction of milk composition from MIR spectral data: A review.

Food chemistry·2024
Same author

Amino Acid Composition of Dried Bovine Dairy Powders from a Range of Product Streams.

Foods (Basel, Switzerland)·2024
Same journal

Active Pocket Engineering of d-Tagatose 4-Epimerase for Improved Catalytic Performance and Efficient Cascade Synthesis of d-Tagatose from d-Glucose.

Journal of agricultural and food chemistry·2026
Same journal

A Novel Cold-Adapted and Heat-Resistant Alginate Lyase: Unveiling Its Characteristics and Mechanism of Thermostability.

Journal of agricultural and food chemistry·2026
Same journal

Targeting the V-ATPase A Subunit in <i>Phytophthora sojae</i>: Discovery of Compound <b>A15</b>.

Journal of agricultural and food chemistry·2026
Same journal

Discovery of Novel Pyrazole-Benzothiazine Hybrids as Potential HPPD Inhibitors.

Journal of agricultural and food chemistry·2026
Same journal

Structural Regulation of Lignin Using an Al<sup>3+</sup>/Zn<sup>2+</sup> Bimetallic Lewis Acid System to Enhance Enzymatic Saccharification.

Journal of agricultural and food chemistry·2026
Same journal

Comparative NMR-Based Metabolomic and Functional Assessment of Fruit and Vegetable Extracts under Regenerative Agricultural Practices.

Journal of agricultural and food chemistry·2026
See all related articles

Related Experiment Video

Updated: Jan 22, 2026

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection
11:57

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection

Published on: May 17, 2011

18.7K

Opportunities and Challenges Using Non-targeted Methods for Food Fraud Detection.

Boyan Gao1, Stephen E Holroyd2, Jeffrey C Moore3

  • 1Institute of Food and Nutraceutical Science, School of Agriculture and Biology , Shanghai Jiao Tong University , Shanghai 200240 , People's Republic of China.

Journal of Agricultural and Food Chemistry
|July 20, 2019
PubMed
Summary
This summary is machine-generated.

Non-targeted methods offer advanced food fraud detection using analytical techniques. This perspective clarifies their definitions, development, validation, and application in food and agriculture, addressing current challenges.

Keywords:
chemometricsfood fraudnon-targeted methodsuntargeted methods

More Related Videos

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry
08:56

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

1.2K
Quasi-metagenomic Analysis of Salmonella from Food and Environmental Samples
06:12

Quasi-metagenomic Analysis of Salmonella from Food and Environmental Samples

Published on: October 25, 2018

9.1K

Related Experiment Videos

Last Updated: Jan 22, 2026

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection
11:57

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection

Published on: May 17, 2011

18.7K
Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry
08:56

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Published on: November 22, 2024

1.2K
Quasi-metagenomic Analysis of Salmonella from Food and Environmental Samples
06:12

Quasi-metagenomic Analysis of Salmonella from Food and Environmental Samples

Published on: October 25, 2018

9.1K

Area of Science:

  • Analytical Chemistry
  • Food Science
  • Agricultural Science

Background:

  • Non-targeted methods are increasingly popular in food fraud detection.
  • Analytical instrumentation techniques underpin these methods.
  • Confusion persists regarding the precise application and interpretation of non-targeted testing.

Purpose of the Study:

  • To clarify definitions and terminology associated with non-targeted testing.
  • To outline the procedures for developing and validating non-targeted analytical methods.
  • To discuss the opportunities and challenges in applying non-targeted methods for food fraud detection.

Main Methods:

  • Review and synthesis of current literature on non-targeted analytical methods.
  • Discussion of various analytical instrumentation techniques.
  • Exploration of data analysis strategies for non-targeted datasets.

Main Results:

  • Provides a comprehensive overview of non-targeted testing principles.
  • Highlights recent advancements in analytical techniques and data interpretation.
  • Identifies key areas for future research and development.

Conclusions:

  • Non-targeted methods represent a significant advancement in food fraud detection.
  • Standardized validation and clear definitions are crucial for reliable application.
  • Continued research is needed to overcome existing challenges and maximize potential.